Latest Issue
HIGH CONFLICT 2024-02-01
GLP-1 gastroparesis FDA

## The Disconnect #1: Paralyzed Stomachs and the FDA Lag

The FDA says Ozempic is "well-tolerated." Reddit says their stomachs have stopped moving. Both are technically "true," but one is 18 months late to the party.

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Evidence Summary
FDA "Transient and mild" Tier 0
NEJM 8.4% nausea, 0 gastroparesis Tier 1
Reddit 400+ gastroparesis reports Tier 5
All Issues
HIGH CONFLICT 2024-02-01 GLP-1 gastroparesis

### #1: Paralyzed Stomachs and the FDA Lag

The FDA says Ozempic is "well-tolerated." Reddit says their stomachs have stopped moving. Both are technically "true," but one is 18 months late to the party.

3 sources, 3 tiers
MEDIUM CONFLICT 2024-02-08 supplements berberine gut-health

### #2: "Nature's Ozempic" Is Destroying Gut Biomes

Berberine went viral as "Nature's Ozempic." TikTok says it works. The clinical data is more complicated -- and nobody's talking about what it does to your microbiome long-term.

5 sources, 4 tiers
HIGH CONFLICT 2024-02-15 mental-health SSRIs withdrawal

### #3: The SSRI Withdrawal Problem Nobody Measured

Clinical trials for antidepressants last 8-12 weeks. Patients take them for years. Nobody studied what happens when you stop -- until patients started documenting it themselves.

7 sources, 4 tiers
LOW CONFLICT 2024-02-22 supplements vitamin-D

### #4: Vitamin D -- The Supplement That Actually Has Evidence

For once, the clinical trials and the internet mostly agree. Vitamin D supplementation has solid evidence for deficiency correction. Here's where they still diverge: dosing.

9 sources, 3 tiers
HIGH CONFLICT 2024-02-29 hormones testosterone TRT

### #5: The Testosterone Clinic Pipeline

Online clinics prescribe testosterone to anyone with "low energy." The reference ranges keep getting wider. The clinical evidence for TRT in borderline cases is thinner than the marketing suggests.

6 sources, 5 tiers

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