stemedb/uat/consumer-health/glp1-muscle-loss-contradiction.md
jordan 8f6506b70a feat: Aphoria scan modes + stemedb-ontology crate + consumer health UAT
Major additions:
- Staged scanning modes (working tree, staged, committed) with git integration
- Drift detection for baseline vs current state comparisons
- Hosted API handlers for policy CRUD operations via StemeDB API
- stemedb-ontology crate with domain definitions and medical extractors
- Consumer health vertical UAT scenarios (GLP-1, gastroparesis, etc.)
- Aphoria development skill documentation

Code organization:
- Split large files into focused modules to stay under 500-line limit
- Extracted config tests, episteme helpers/drift/aliases, API helpers

Co-Authored-By: Claude Opus 4.5 <noreply@anthropic.com>
2026-02-04 21:57:33 -07:00

151 lines
3.6 KiB
Markdown

# UAT: Muscle Loss Contradiction (Skeptic Lens)
**Date:** YYYY-MM-DD
**Feature:** First-Class Contradiction
**Status:** [ ] PASS / [ ] FAIL / [ ] BLOCKED
## Scenario
Two peer-reviewed studies report opposing conclusions on GLP-1 agonist muscle-sparing effects:
- Study A (PMID_38001234): "Significant muscle loss observed"
- Study B (PMID_38005678): "Muscle mass preserved vs placebo"
Both are Tier 1 (Clinical) sources with similar confidence. The Skeptic Lens should surface both claims without forcing resolution.
## Acceptance Criteria
| Criterion | Expected | Met? |
|-----------|----------|------|
| Both claims coexist | Neither deleted | [ ] |
| Conflict score | >= 0.88 | [ ] |
| Status | "Contested" | [ ] |
| Claims array | 2 distinct values | [ ] |
| No hallucinated average | No "moderate loss" | [ ] |
## Test Matrix
| Step | Action | Expected | Actual | Status |
|------|--------|----------|--------|--------|
| 1 | Ingest Study A claim | Hash returned | | [ ] |
| 2 | Ingest Study B claim | Hash returned | | [ ] |
| 3 | Query skeptic lens | Both claims returned | | [ ] |
| 4 | Check conflict_score | >= 0.88 | | [ ] |
| 5 | Check status | Contested | | [ ] |
| 6 | Verify no averaging | 2 distinct ObjectValues | | [ ] |
## Setup Commands
```bash
# Start StemeDB
cargo run --bin stemedb-api &
# Wait for startup
sleep 2
```
## Test Commands
### Step 1: Ingest Study A (muscle loss = true)
```bash
curl -X POST http://localhost:18180/v1/assertions \
-H "Content-Type: application/json" \
-d '{
"subject": "Semaglutide:MuscleMass",
"predicate": "muscle_sparing_effect",
"object": {"Boolean": false},
"confidence": 0.85,
"source_class": "Clinical",
"source_hash": "0000000000000000000000000000000000000000000000000000000000000001"
}'
```
**Expected:** `{"hash": "..."}`
**Actual:**
**Status:** [ ]
### Step 2: Ingest Study B (muscle loss = false)
```bash
curl -X POST http://localhost:18180/v1/assertions \
-H "Content-Type: application/json" \
-d '{
"subject": "Semaglutide:MuscleMass",
"predicate": "muscle_sparing_effect",
"object": {"Boolean": true},
"confidence": 0.82,
"source_class": "Clinical",
"source_hash": "0000000000000000000000000000000000000000000000000000000000000002"
}'
```
**Expected:** `{"hash": "..."}`
**Actual:**
**Status:** [ ]
### Step 3: Query with Skeptic Lens
```bash
curl "http://localhost:18180/v1/skeptic?subject=Semaglutide:MuscleMass&predicate=muscle_sparing_effect"
```
**Expected:**
```json
{
"status": "Contested",
"conflict_score": 0.88,
"claims": [
{"value": {"Boolean": false}, "weight_share": 0.51, "assertion_count": 1},
{"value": {"Boolean": true}, "weight_share": 0.49, "assertion_count": 1}
],
"candidates_count": 2
}
```
**Actual:**
**Status:** [ ]
### Step 4: Verify Conflict Score
From Step 3 response, extract `conflict_score`.
**Expected:** >= 0.88
**Actual:**
**Status:** [ ]
### Step 5: Verify Status
From Step 3 response, check `status` field.
**Expected:** "Contested"
**Actual:**
**Status:** [ ]
### Step 6: Verify No Averaging
Confirm `claims` array contains exactly 2 entries with distinct `Boolean` values.
NO claim should have an averaged or interpolated value.
**Expected:** 2 distinct ObjectValues (true and false)
**Actual:**
**Status:** [ ]
## Sign-Off Checklist
- [ ] Both studies ingested successfully
- [ ] Skeptic lens returns both claims
- [ ] Conflict score >= 0.88
- [ ] Status is "Contested"
- [ ] No hallucinated average value
- [ ] Neither original claim deleted
## Notes
*Record any observations, edge cases, or issues here.*
---
**Tester:**
**Date:**
**Result:**